MoPho, the fun mobile printing app from?Penguin Digital?(with the ridiculous name), is rolling an update today that may include one its hottest features yet: 1 cent Instagram prints. The app, which allows you to smack your photos onto mousepads, mugs, key chains, t-shirts, and more - sort of like a mobile CafePress shop - is adding support for Instagram today. The option now joins Facebook, Flickr, and Picasa in the selection of third-party services you can pull from. To kick off the launch of the updated app, MoPho is offering 1 cent Instagram prints - to be clear, that's printed out photos, not customized consumer goods. However, you can choose to decorate a number of new products with your Instagram photos, too, including things like keepsake boxes, square canvases, coasters, iPhone cases, and more. You can even make yourself some temporary tattoos from the photos. (Ha. Oh, that sunset photo on my arm? Yeah, it's a tattoo from my Instagram collection.)
ETF trends are guidelines used by traders to identify market entry and exit points, in other words when to buy and when to sell. ETFs are ?Exchange-Traded Funds?. They are something like mutual funds, but there are differences.
Funds, of all kinds, give small investors access to a wider range of investment choices. The funds are managed professionally and diversified. Assets held within the fund may include stocks, bonds and other securities. So, it resembles a smart investor?s portfolio.
Instead of being held by a single investor, funds are held by a large number of investors. The accumulated pool of money is invested and the profits, which ideally are larger than a single small investor could make alone, are shared.
A mutual fund?s net asset value (NAV) is calculated once a day. The value or price of an ETF will change throughout the day, as shares are bought and sold.
As little as one share of an ETF can be purchased and day trading is possible.
Mutual funds are typically held for long periods of time and a minimum number of shares must be purchased in order to buy in.
Trends are used in all markets, but the trends that are most important to an ETF investor are 50-day and 200-day trends. A smart investor identifies the trend before he or she buys in. Simply put, a 50 day trend would look at the average price of the ETF over the last 50 days. A 200 day trend would look at the average over the last 200 days.
A trend can cover any time periods. When analysts say that stocks historically earned average returns of 10-12%, they were looking at very long trends. Obviously, the historical trend did not hold true in the last several years.
Investors have different strategies when they are using trends, but a good rule of thumb is to buy in when you see an upward trend for the last 200 days and start thinking about selling if the value falls below the 50 day average. If it falls below the 200-day average, then the fund is trending downwards and it?s a good time to sell.
If you decide to use trends, you need to decide what you are going to do before you buy. How much are you willing to lose? If you buy in today and start making money, you are likely to lose some of those profits eventually.
Knowing when to sell is the key to making profits with ETFs. There?s no guarantee, but analyzing the trends should help you do that.
Mayo Clinic researchers building melanoma vaccine to combat skin cancerPublic release date: 19-Mar-2012 [ | E-mail | Share ]
Contact: Robert Nellis newsbureau@mayo.edu 507-284-5005 Mayo Clinic
ROCHESTER, Minn. -- Mayo Clinic researchers have trained mouse immune systems to eradicate skin cancer from within, using a genetic combination of human DNA from melanoma cells and a cousin of the rabies virus. The strategy, called cancer immunotherapy, uses a genetically engineered version of the vesicular stomatitis virus to deliver a broad spectrum of genes derived from melanoma cancer cells directly into tumors. In early studies, 60 percent of tumor-burdened mice were cured in fewer than three months and with minimal side effects. Results of the latest study appear this week in the journal Nature Biotechnology.
"We believe that this new technique will help us to identify a whole new set of genes that encode antigens that are important in stimulating the immune system to reject cancer. In particular, we have seen that several proteins need to be expressed together to generate the most effective rejection of the tumors in mice," says Richard Vile, Ph.D., a Mayo Clinic researcher in the Department of Molecular Medicine and a coauthor of the study, along with Jose Pulido, M.D., a Mayo Clinic ophthalmologist and ocular oncologist.
Dr. Vile's success with melanoma adds to Mayo Clinic's growing portfolio of experimental cancer vaccines, which includes an active clinical trial of vesicular stomatitis vaccines for liver cancers. Future studies could include similar vaccines for more aggressive cancers, such as lung, brain and pancreatic.
"I do believe we can create vaccines that will knock them off one by one," Dr. Vile says. "By vaccinating against multiple proteins at once, we hope that we will be able to treat both the primary tumor and also protect against recurrence."
The immune system functions on a seek-and-destroy platform and has fine-tuned its capacity to identify viral invaders such as vesicular stomatitis virus. Part of the appeal of building cancer vaccines from the whole spectrum of tumor DNA is that tumors can adapt to the repeated attacks of a healthy immune system and display fewer antigens (or signposts) that the immune system can identify.
Cancers can learn to hide from a normal immune system, but appear unable to escape an immune system trained by the vesicular stomatitis virus with the wide range of DNA used in the library approach.
"Nobody knows how many antigens the immune system can really see on tumor cells," says Dr. Vile. "By expressing all of these proteins in highly immunogenic viruses, we increased their visibility to the immune system. The immune system now thinks it is being invaded by the viruses, which are expressing cancer-related antigens that should be eliminated."
Much immunotherapy research has slowed because of researchers' inability to isolate a sufficiently diverse collection of antigens in tumor cells. Tumors in these scenarios are able to mutate and reestablish themselves in spite of the body's immune system.
The study was a Mayo collaboration with professors Alan Melcher and Peter Selby at the Leeds Institute of Molecular Medicine, University of Leeds, U.K. They were also co-authors.
###
Other coauthors of the article are Timothy Kottke; Jill Thompson; Feorillo Galivo, Ph.D; Rosa Maria Diaz; Diana Rommelfanger-Konkol; Elizabeth Ilett; and Larry Pease, Ph.D., all of Mayo Clinic; Hardev Pandha, M.D., University of Surrey, Guildford, U.K.; Phonphimon Wongthida, Ph.D., Department of Virology and Cell Technology at the National Center for Genetic Engineering and Biotechnology, Pathumthani, Thailand; and Kevin Harrington, Ph.D., Institute of Cancer Research, London, U.K.
The study was funded by the Richard M. Schulze Family Foundation, Mayo Clinic, Cancer Research UK, the National Institutes of Health, and a grant from Terry and Judith Paul.
About Mayo Clinic
Mayo Clinic is a nonprofit worldwide leader in medical care, research and education for people from all walks of life. For more information, visit http://www.mayoclinic.org/about and www.mayoclinic.org/news.
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Mayo Clinic researchers building melanoma vaccine to combat skin cancerPublic release date: 19-Mar-2012 [ | E-mail | Share ]
Contact: Robert Nellis newsbureau@mayo.edu 507-284-5005 Mayo Clinic
ROCHESTER, Minn. -- Mayo Clinic researchers have trained mouse immune systems to eradicate skin cancer from within, using a genetic combination of human DNA from melanoma cells and a cousin of the rabies virus. The strategy, called cancer immunotherapy, uses a genetically engineered version of the vesicular stomatitis virus to deliver a broad spectrum of genes derived from melanoma cancer cells directly into tumors. In early studies, 60 percent of tumor-burdened mice were cured in fewer than three months and with minimal side effects. Results of the latest study appear this week in the journal Nature Biotechnology.
"We believe that this new technique will help us to identify a whole new set of genes that encode antigens that are important in stimulating the immune system to reject cancer. In particular, we have seen that several proteins need to be expressed together to generate the most effective rejection of the tumors in mice," says Richard Vile, Ph.D., a Mayo Clinic researcher in the Department of Molecular Medicine and a coauthor of the study, along with Jose Pulido, M.D., a Mayo Clinic ophthalmologist and ocular oncologist.
Dr. Vile's success with melanoma adds to Mayo Clinic's growing portfolio of experimental cancer vaccines, which includes an active clinical trial of vesicular stomatitis vaccines for liver cancers. Future studies could include similar vaccines for more aggressive cancers, such as lung, brain and pancreatic.
"I do believe we can create vaccines that will knock them off one by one," Dr. Vile says. "By vaccinating against multiple proteins at once, we hope that we will be able to treat both the primary tumor and also protect against recurrence."
The immune system functions on a seek-and-destroy platform and has fine-tuned its capacity to identify viral invaders such as vesicular stomatitis virus. Part of the appeal of building cancer vaccines from the whole spectrum of tumor DNA is that tumors can adapt to the repeated attacks of a healthy immune system and display fewer antigens (or signposts) that the immune system can identify.
Cancers can learn to hide from a normal immune system, but appear unable to escape an immune system trained by the vesicular stomatitis virus with the wide range of DNA used in the library approach.
"Nobody knows how many antigens the immune system can really see on tumor cells," says Dr. Vile. "By expressing all of these proteins in highly immunogenic viruses, we increased their visibility to the immune system. The immune system now thinks it is being invaded by the viruses, which are expressing cancer-related antigens that should be eliminated."
Much immunotherapy research has slowed because of researchers' inability to isolate a sufficiently diverse collection of antigens in tumor cells. Tumors in these scenarios are able to mutate and reestablish themselves in spite of the body's immune system.
The study was a Mayo collaboration with professors Alan Melcher and Peter Selby at the Leeds Institute of Molecular Medicine, University of Leeds, U.K. They were also co-authors.
###
Other coauthors of the article are Timothy Kottke; Jill Thompson; Feorillo Galivo, Ph.D; Rosa Maria Diaz; Diana Rommelfanger-Konkol; Elizabeth Ilett; and Larry Pease, Ph.D., all of Mayo Clinic; Hardev Pandha, M.D., University of Surrey, Guildford, U.K.; Phonphimon Wongthida, Ph.D., Department of Virology and Cell Technology at the National Center for Genetic Engineering and Biotechnology, Pathumthani, Thailand; and Kevin Harrington, Ph.D., Institute of Cancer Research, London, U.K.
The study was funded by the Richard M. Schulze Family Foundation, Mayo Clinic, Cancer Research UK, the National Institutes of Health, and a grant from Terry and Judith Paul.
About Mayo Clinic
Mayo Clinic is a nonprofit worldwide leader in medical care, research and education for people from all walks of life. For more information, visit http://www.mayoclinic.org/about and www.mayoclinic.org/news.
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Gold Investments - Some of the Hottest Alternative Investment Opportunities Today
Gold investments are among the best alternative investments currently available, especially in the context of the economic insecurity that still affects many world economies.
Why It?s Worth Investing in Gold
Gold is seen as a great investment whenever there is the threat of a raising inflation, as it helps people convert volatile assets into a precious metal that will continue to be valuable regardless of what befalls the economy.
But gold also makes for a possibly good investment for those who seek to get a nice return on their investments. Short term investments in gold, however, do not tend to be as rewarding as other investments, since the price of gold is somewhat more stable than that of say silver, which rises and falls more often and more significantly.
But when it comes to long-term alternative investments, gold is considered by many to be unrivalled. That?s because gold has been since time immemorial prized for its beauty and value, and will continue to be so for years to come regardless of what happens with the financial markets.
Ads by GoogleUnless an unimaginably vast deposit of gold is found soon ? which is unlikely, considering that right known gold deposits are actually dwindling ? gold will continue to retain its high value, which makes the precious metal ideal for an alternative investment.
Gold is venerated and desired and these contribute to making it one of the most secure things to invest it. And besides, when you invest in gold you can actually own the material, which may give you a pleasure than not all the money in the world can buy.
Gold?s Rivals: Silver and Platinum
Gold clearly dominates the other precious metals. Silver is more volatile and much less valuable, its market being much smaller than that of gold. This makes silver investments potentially good for quick gains, but ultimately unreliable for long-term serious investments. And besides, silver takes more storage space than gold.
Platinum, on the other hand, is more valuable, but also more difficult to handle. Investments in platinum are infamous for their high risk, and only few experts really carry them out. What?s more, unlike gold, platinum is hard to convert into cash.
How to Invest
Gold investments can be some of the most rewarding alternative investments, especially when they are significant. But even investing in small quantities of gold can be rewarding.
You can invest in gold by buying gold bullion or gold coins. Alternatively, you can buy stock in gold mining or gold producing companies, as well as gold futures contracts. Some say though that the best gold investments are those in which you buy and own the gold yourself.
Investing in gold is definitely one of the hottest alternative investment opportunities today. But to invest successfully you need to compare investment opportunities and to go with the one your calculations point you to.
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March 19, 2012
?Tags:?Gold Investments - Some of the Hottest Alternative Investment Opportunities Today ?Posted?in:?gold investment
NASHVILLE, TN - MARCH 16: Victor Rudd Jr. #2 of the South Florida Bulls celebrates after a play against the Temple Owls during the second round of the 2012 NCAA Men's Basketball Tournament at Bridgestone Arena on March 16, 2012 in Nashville, Tennessee. (Photo by Kevin C. Cox/Getty Images)
An important mistake organizations make when running online business is usually to assume the website is correctly optimized or perhaps worse yet, not see the importance of web site advertising and marketing. Probably the most beautifully-crafted, pretty, progressive and simply navigable web site is usually pointless in case it?s impossible to see it. Around 75Percent relating to web users rarely go beyond the 1st website for major search engines like yahoo due to less than FourPer cent looking past internet page 3 or more. Simply, which means your website is absolutely invisible if it does not enter the most notable three internet pages due to major google page rank suitable intended for firms that want to be a success.
Advertise Or Go away
Failure to advertise your website assures this stays without anyone?s knowledge, most likely going to never start to see the lighting of day time. One of the most frustrating issue a lot of companies do is always to commit a lot of money about web developers while disregarding in order to dash on an advertising and marketing group. A website which makes page one with the Yahoo and google search engine rankings will probably be worth the weight within gold. Bear in mind, if you can?t appropriately advertise your web site, be assured, the rival may advertise their own making page one of the search engines. This may in essence wipe get you started.
There are a number of different types of web-site advertising and marketing for example banner advertising as well as Pay-per-click (PPC) promotion. This tends to cost a lot of money and might not succeed. Search engine ranking (Seo optimisation) on the other hand, is pretty affordable which is a surefire method to get your site noticed online. Web optimization it?s essentially a technique for employing strategies including adding hyperlinks and carefully put key phrases as part of your web-site in a way that interests the attention regarding search engine spiders who search the internet. A rightly engineered Website seo advertising campaign will cost little or no which is more likely to shoot your web site to the top with the search engine results.
Submissions are master in terms of Website seo. A lot more firms naiively rely on keyword phrase filling with regards to advertising and marketing their own internet websites. They?re of the opinion a Four% key phrase denseness is the foremost way of achieving success. It becomes an really flawed method since Google along with yahoo and google penalize these practices with indicating the web page to become spammy. Just what a lot of directory submissions don?t understand is the fact search engines like google examine every one way links thus to their top rated positioning web-sites from the same market. Top rated ranking web sites are apt to have a keyword denseness which is between 1-2%. Because of this sites which has an a lot higher density are red-flagged and started the rankings.
We make getting a qualified, expert Kitchen remodeling specialists easy! Let us assist you with your project. Our experts in Hollywood can design, renovate, and make a Kitchen for your house! CA Kitchen Remodeling makes remodeling projects easy! Simply request a free of charge estimate and make the Kitchen you?ve always dreamt of!
Remodeling your kitchen area is often a great remedy to update the inside look of your property and make your kitchen room area an improved match to your lifestyle and needs. Since there are numerous actions with some kitchen area remodeling undertaking that could become difficult, it is important that you make detailed decisions before you begin. With regards to kitchen?s remodeling, cautious and detailed preparing ought to be a must.
We will allow you to sort through the endless possibilities of layouts, styles, lighting, fixtures, accessories and a lot more ? transforming your home kitchen right into a masterpiece that you simply as well as your household will love for life. A kitchen renovation is really a complex job that is certainly hinged on many distinct variables, involving everything from workspace preparing and color scheme choice to time and budget factors.
Remodeling your kitchen in Hollywood doesn?t have to be expensive. Whether you would like to assemble & install your kitchen cabinets yourself, or have us do all the work, CA Kitchen Remodeling Hollywood makes it possible for you to get a new kitchen with beautiful all-wood cabinets at a lower price. That?s under the property improvement stores. We provide a lot of options of kitchen cabinet sizes, styles, colors and accessories. We want to help you create a kitchen of beauty and efficiency.
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MoPho, the fun mobile printing app from?Penguin Digital?(with the ridiculous name), is rolling an update today that may include one its hottest features yet: 1 cent Instagram prints. The app, which allows you to smack your photos onto mousepads, mugs, key chains, t-shirts, and more - sort of like a mobile CafePress shop - is adding support for Instagram today. The option now joins Facebook, Flickr, and Picasa in the selection of third-party services you can pull from. To kick off the launch of the updated app, MoPho is offering 1 cent Instagram prints - to be clear, that's printed out photos, not customized consumer goods. However, you can choose to decorate a number of new products with your Instagram photos, too, including things like keepsake boxes, square canvases, coasters, iPhone cases, and more. You can even make yourself some temporary tattoos from the photos. (Ha. Oh, that sunset photo on my arm? Yeah, it's a tattoo from my Instagram collection.) 
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March 19, 2012
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Tags:?Gold Investments - Some of the Hottest Alternative Investment Opportunities Today ?Posted?in:?gold investment
